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Analysis of large deletion mutations induced by abasic site analog in human cells
BACKGROUND: Abasic sites are formed spontaneously and by nucleobase chemical modifications and base excision repair. A chemically stable abasic site analog was site-specifically introduced into replicable plasmid DNAs, which were transfected into human U2OS cells. The amplified DNAs were recovered f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199760/ https://www.ncbi.nlm.nih.gov/pubmed/30386442 http://dx.doi.org/10.1186/s41021-018-0110-7 |