Cargando…

Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania

BACKGROUND: Children are subject to varying drug pharmacokinetics which influence plasma drug levels, and hence treatment outcomes especially for drugs like efavirenz whose plasma concentrations are directly related to treatment outcomes. This study is aimed at determining plasma efavirenz concentra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sungi, Selemani Saidi, Ngaimisi, Eliford, Ulenga, Nzovu, Sasi, Philip, Mugusi, Sabina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199790/ https://www.ncbi.nlm.nih.gov/pubmed/30352627 http://dx.doi.org/10.1186/s40360-018-0258-6

Ejemplares similares

Adherence to combination antiretroviral therapy among orphaned children in Dar es Salaam, Tanzania
por: Mugusi, Sabina F., et al.
Publicado: (2019)

The prevalence and pattern of antibiotic prescription among insured patients in Dar es Salaam Tanzania
por: Khalfan, Mohamed Ally, et al.
Publicado: (2021)

Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania
por: Mugusi, Sabina, et al.
Publicado: (2012)

Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype
por: Kitabi, Eliford Ngaimisi, et al.
Publicado: (2018)

Community delivery of antiretroviral drugs: A non-inferiority cluster-randomized pragmatic trial in Dar es Salaam, Tanzania
por: Geldsetzer, Pascal, et al.
Publicado: (2018)

Lipodystrophy among HIV-Infected Patients Attending Care and Treatment Clinics in Dar es Salaam
por: Njelekela, Marina, et al.
Publicado: (2017)

Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin
por: Mugusi, Sabina, et al.
Publicado: (2018)

Intra-cluster correlation estimates for HIV-related outcomes from care and treatment clinics in Dar es Salaam, Tanzania
por: Barnhart, Dale, et al.
Publicado: (2016)

School readiness among children born to women living with HIV in Dar es Salaam, Tanzania: a cohort study protocol
por: Perumal, Nandita, et al.
Publicado: (2022)

Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations
por: Mugusi, Sabina, et al.
Publicado: (2020)

Prevalence of obesity and associated risk factors among adults in Kinondoni municipal district, Dar es Salaam Tanzania
por: Shayo, Grace A, et al.
Publicado: (2011)

Effect of Improved access to Antiretroviral Therapy on clinical characteristics of patients enrolled in the HIV care and treatment clinic, at Muhimbili National Hospital (MNH), Dar es Salaam, Tanzania
por: Mugusi, Sabina F, et al.
Publicado: (2010)

The impact of community health worker-led home delivery of antiretroviral therapy on virological suppression: a non-inferiority cluster-randomized health systems trial in Dar es Salaam, Tanzania
por: Geldsetzer, Pascal, et al.
Publicado: (2017)

Factors for late initiation of antenatal care in Dar es Salaam, Tanzania: A qualitative study
por: Mgata, Saidi, et al.
Publicado: (2019)

Prediction of plasma efavirenz concentrations among HIV-positive patients taking efavirenz-containing combination antiretroviral therapy
por: Huang, Sung-Hsi, et al.
Publicado: (2017)

Assessing Environmental Enteric Dysfunction via Multiplex Assay and its Relation to Infant Growth Among HIV-Exposed Infants in Dar es Salaam, Tanzania
por: Lauer, Jacqueline, et al.
Publicado: (2022)

Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations
por: Ngaimisi, Eliford, et al.
Publicado: (2013)

Challenges in diagnosing paediatric malaria in Dar es Salaam, Tanzania
por: Strøm, Gro EA, et al.
Publicado: (2013)

Urban lymphatic filariasis in the metropolis of Dar es Salaam, Tanzania
por: Mwakitalu, Mbutolwe E, et al.
Publicado: (2013)

Challenges in diagnosing pediatric malaria in Dar es Salaam, Tanzania
por: Strom, Gro EA, et al.
Publicado: (2012)

Adherence to antiretroviral therapy among HIV infected children measured by caretaker report, medication return, and drug level in Dar Es Salaam, Tanzania
por: Mghamba, Frida William, et al.
Publicado: (2013)

Predictors of mortality among adolescents and young adults living with HIV on antiretroviral therapy in Dar es Salaam, Tanzania: a retrospective cohort study
por: Amour, Maryam A., et al.
Publicado: (2022)

Abstracts of the 9th Tanzania Health Summit: Dar Es Salaam, Tanzania.
Publicado: (2023)

Community health workers to improve uptake of maternal healthcare services: A cluster-randomized pragmatic trial in Dar es Salaam, Tanzania
por: Geldsetzer, Pascal, et al.
Publicado: (2019)

Undernutrition among HIV-positive children in Dar es Salaam, Tanzania: antiretroviral therapy alone is not enough
por: Sunguya, Bruno F, et al.
Publicado: (2011)

Masculine attitudes of superiority deter men from accessing antiretroviral therapy in Dar es Salaam, Tanzania
por: Nyamhanga, Tumaini M., et al.
Publicado: (2013)

Incidence and Risk Factors for Overweight and Obesity after Initiation of Antiretroviral Therapy in Dar es Salaam, Tanzania
por: Kintu, Alexander, et al.
Publicado: (2018)

The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment
por: Maganda, Betty A, et al.
Publicado: (2015)

Informal Urban Settlements and Cholera Risk in Dar es Salaam, Tanzania
por: Penrose, Katherine, et al.
Publicado: (2010)

Determinants of acceptance of cervical cancer screening in Dar es Salaam, Tanzania
por: Kahesa, Crispin, et al.
Publicado: (2012)

Pattern and risk factors for childhood injuries in Dar es Salaam, Tanzania
por: Moshiro, Robert, et al.
Publicado: (2021)

HIV risk and pre-exposure prophylaxis interest among female bar workers in Dar es Salaam: cross-sectional survey
por: Harling, Guy, et al.
Publicado: (2019)

Trends in Hospitalisation for Human Immunodeficiency Virus in a Tertiary Hospital in Dar es Salaam, Tanzania: A Case study
por: Shayo, Grace A, et al.
Publicado: (2020)

Acceptability and adherence to Isoniazid preventive therapy in HIV-infected patients clinically screened for latent tuberculosis in Dar es Salaam, Tanzania
por: Shayo, Grace A., et al.
Publicado: (2015)

Risk of Cardiovascular Events Among Patients Initiating Efavirenz-Containing Versus Efavirenz-Free Antiretroviral Regimens
por: Rosenblatt, Lisa, et al.
Publicado: (2016)

Prevalence and Correlates of Cardio-Metabolic Risk Factors Among Regular Street Food Consumers in Dar es Salaam, Tanzania
por: Kagaruki, Gibson B, et al.
Publicado: (2021)

Genetic and non‐genetic factors influencing efavirenz population pharmacokinetics among human immunodeficiency virus‐1‐infected children in Ethiopia
por: Chala, Adugna, et al.
Publicado: (2023)

Anemia at the Initiation of Tuberculosis Therapy Is Associated with Delayed Sputum Conversion among Pulmonary Tuberculosis Patients in Dar-es-Salaam, Tanzania
por: Nagu, Tumaini J., et al.
Publicado: (2014)

Patterns of sexually transmitted infections in adolescents and youth in Dar es Salaam, Tanzania
por: Chalamilla, Guerino, et al.
Publicado: (2006)

Prevalence of helmet use among motorcycle users in Dar Es Salaam, Tanzania
por: Kauky, Cosmas George, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n64afn9gj9c1dc3ciboecg1ntb