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Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS Gene

BACKGROUND: KRAS genotyping in tumor samples is a decisive clinical test for the anti-EGFR therapy management. However, the complexity of KRAS mutation landscape across different cancer types and the mosaic effect caused by cancer cellularity and heterogeneity make the choice of KRAS genotyping meth...

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Detalles Bibliográficos
Autores principales:	Zhang, Qunfeng, Du, Yiqiao, Zhang, Xinju, Kang, Zhihua, Guan, Ming, Wu, Zhiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199860/ https://www.ncbi.nlm.nih.gov/pubmed/30406144 http://dx.doi.org/10.1155/2018/8727941

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