Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018

Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Becker, Sören L., Berger, Fabian K., Feldner, Susanne K., Karliova, Irem, Haber, Manfred, Mellmann, Alexander, Schäfers, Hans-Joachim, Gärtner, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199865/
https://www.ncbi.nlm.nih.gov/pubmed/30352639
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.42.1800540
Descripción
Sumario:Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.

Ejemplares similares