Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018

Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, fr...

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Autores principales: Becker, Sören L., Berger, Fabian K., Feldner, Susanne K., Karliova, Irem, Haber, Manfred, Mellmann, Alexander, Schäfers, Hans-Joachim, Gärtner, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199865/
https://www.ncbi.nlm.nih.gov/pubmed/30352639
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.42.1800540
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author Becker, Sören L.
Berger, Fabian K.
Feldner, Susanne K.
Karliova, Irem
Haber, Manfred
Mellmann, Alexander
Schäfers, Hans-Joachim
Gärtner, Barbara
author_facet Becker, Sören L.
Berger, Fabian K.
Feldner, Susanne K.
Karliova, Irem
Haber, Manfred
Mellmann, Alexander
Schäfers, Hans-Joachim
Gärtner, Barbara
author_sort Becker, Sören L.
collection PubMed
description Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.
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spelling pubmed-61998652018-11-07 Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018 Becker, Sören L. Berger, Fabian K. Feldner, Susanne K. Karliova, Irem Haber, Manfred Mellmann, Alexander Schäfers, Hans-Joachim Gärtner, Barbara Euro Surveill Rapid Communication Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks. European Centre for Disease Prevention and Control (ECDC) 2018-10-18 /pmc/articles/PMC6199865/ /pubmed/30352639 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.42.1800540 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Becker, Sören L.
Berger, Fabian K.
Feldner, Susanne K.
Karliova, Irem
Haber, Manfred
Mellmann, Alexander
Schäfers, Hans-Joachim
Gärtner, Barbara
Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title_full Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title_fullStr Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title_full_unstemmed Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title_short Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018
title_sort outbreak of burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, germany, august to september 2018
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199865/
https://www.ncbi.nlm.nih.gov/pubmed/30352639
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.42.1800540
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