A Purinergic P2 Receptor Family-Mediated Increase in Thrombospondin-1 Bolsters Synaptic Density and Epileptic Seizure Activity in the Amygdala-Kindling Rat Model

Previous studies suggested that the thrombospondin-1/transforming growth factor-β1 (TSP-1/TGF-β1) pathway might be critical in synaptogenesis during development and that the purinergic P2 receptor family could regulate synaptogenesis by modulating TSP-1 signaling. However, it is unclear whether this...

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Detalles Bibliográficos
Autores principales: Sun, Hongliu, Ma, Luyu, Zhang, Yurong, Pan, Xiaohong, Wang, Chaoyun, Zhang, Jinjin, Zhang, Xiuli, Sun, Hongwei, Wang, Qiaoyun, Zhu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199899/
https://www.ncbi.nlm.nih.gov/pubmed/30386206
http://dx.doi.org/10.3389/fncel.2018.00302

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