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Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1(I249/M280) Variant

Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered the primary pathology of MS, but progressive axon...

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Detalles Bibliográficos
Autores principales: Cardona, Sandra M., Kim, Sangwon V., Church, Kaira A., Torres, Vanessa O., Cleary, Ian A., Mendiola, Andrew S., Saville, Stephen P., Watowich, Stephanie S., Parker-Thornburg, Jan, Soto-Ospina, Alejandro, Araque, Pedronel, Ransohoff, Richard M., Cardona, Astrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199958/
https://www.ncbi.nlm.nih.gov/pubmed/30386211
http://dx.doi.org/10.3389/fncel.2018.00365