Cargando…
Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1(I249/M280) Variant
Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered the primary pathology of MS, but progressive axon...
Autores principales: | Cardona, Sandra M., Kim, Sangwon V., Church, Kaira A., Torres, Vanessa O., Cleary, Ian A., Mendiola, Andrew S., Saville, Stephen P., Watowich, Stephanie S., Parker-Thornburg, Jan, Soto-Ospina, Alejandro, Araque, Pedronel, Ransohoff, Richard M., Cardona, Astrid E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199958/ https://www.ncbi.nlm.nih.gov/pubmed/30386211 http://dx.doi.org/10.3389/fncel.2018.00365 |
Ejemplares similares
-
Pharmacological depletion of microglia alleviates neuronal and vascular damage in the diabetic CX3CR1-WT retina but not in CX3CR1-KO or hCX3CR1(I249/M280)-expressing retina
por: Church, Kaira A., et al.
Publicado: (2023) -
Association of chemokine receptor CX3CR1 V249I and T280M polymorphisms with chronic kidney disease
por: Yadav, A. K., et al.
Publicado: (2016) -
Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation
in A CX3CR1-Independent Manner
por: Sarker, Borna, et al.
Publicado: (2022) -
Search for an Association between V249I and T280M CX3CR1 Genetic Polymorphisms, Endothelial Injury and Preeclampsia: The ECLAXIR Study
por: Stepanian, Alain, et al.
Publicado: (2009) -
Fractalkine/CX3CR1 signaling during neuropathic pain
por: Clark, Anna K., et al.
Publicado: (2014)