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Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016

Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated commercial chlorhexidine mouthwash. Genomic analysis identified efflux pump–encodi...

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Detalles Bibliográficos
Autores principales: Leong, Lex E.X., Lagana, Diana, Carter, Glen P., Wang, Qinning, Smith, Kija, Stinear, Tim P., Shaw, David, Sintchenko, Vitali, Wesselingh, Steven L., Bastian, Ivan, Rogers, Geraint B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199994/
https://www.ncbi.nlm.nih.gov/pubmed/30334703
http://dx.doi.org/10.3201/eid2411.171929
Descripción
Sumario:Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated commercial chlorhexidine mouthwash. Genomic analysis identified efflux pump–encoding genes as potential facilitators of bacterial persistence within this biocide.