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Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly
Aging populations experience a decline in adaptive immune system function also known as immunosenesence. Protein nutrition has been shown to stimulate and strengthen the immune system, and such approaches are needed for this growing segment of the population. A controlled, randomized, double blind p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200024/ https://www.ncbi.nlm.nih.gov/pubmed/30386327 http://dx.doi.org/10.3389/fimmu.2018.02254 |
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author | Schaefer, Sara Hettinga, Kasper Arthur Cullor, James German, J. Bruce Henrick, Bethany M. |
author_facet | Schaefer, Sara Hettinga, Kasper Arthur Cullor, James German, J. Bruce Henrick, Bethany M. |
author_sort | Schaefer, Sara |
collection | PubMed |
description | Aging populations experience a decline in adaptive immune system function also known as immunosenesence. Protein nutrition has been shown to stimulate and strengthen the immune system, and such approaches are needed for this growing segment of the population. A controlled, randomized, double blind pilot study was conducted to compare two different protein sources (soy and dairy) as nutritional supplementation to enhance vaccine response. Our objective was to examine the immune stimulating effects of dairy protein subjected to ultraviolet radiation (UV-C) radiation treatment process instead of pasteurization. Participants were 21 healthy individuals over 60 years of age who consumed 6 g of the dairy protein or a comparison, soy isoflavone protein, twice a day for 8 weeks. DTaP vaccine administered at week 4. Non-parametric t-tests revealed a significant increase in Tetanus antibodies in the dairy group compared to the soy group at week 8. These findings suggest additional benefits of UV-C treated unheated dairy protein as a solution to counteract immunosenescence, but warrant further study in elderly and other populations that might benefit from immune system stimulation. |
format | Online Article Text |
id | pubmed-6200024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-62000242018-11-01 Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly Schaefer, Sara Hettinga, Kasper Arthur Cullor, James German, J. Bruce Henrick, Bethany M. Front Immunol Immunology Aging populations experience a decline in adaptive immune system function also known as immunosenesence. Protein nutrition has been shown to stimulate and strengthen the immune system, and such approaches are needed for this growing segment of the population. A controlled, randomized, double blind pilot study was conducted to compare two different protein sources (soy and dairy) as nutritional supplementation to enhance vaccine response. Our objective was to examine the immune stimulating effects of dairy protein subjected to ultraviolet radiation (UV-C) radiation treatment process instead of pasteurization. Participants were 21 healthy individuals over 60 years of age who consumed 6 g of the dairy protein or a comparison, soy isoflavone protein, twice a day for 8 weeks. DTaP vaccine administered at week 4. Non-parametric t-tests revealed a significant increase in Tetanus antibodies in the dairy group compared to the soy group at week 8. These findings suggest additional benefits of UV-C treated unheated dairy protein as a solution to counteract immunosenescence, but warrant further study in elderly and other populations that might benefit from immune system stimulation. Frontiers Media S.A. 2018-10-17 /pmc/articles/PMC6200024/ /pubmed/30386327 http://dx.doi.org/10.3389/fimmu.2018.02254 Text en Copyright © 2018 Schaefer, Hettinga, Cullor, German and Henrick. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Schaefer, Sara Hettinga, Kasper Arthur Cullor, James German, J. Bruce Henrick, Bethany M. Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title | Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title_full | Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title_fullStr | Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title_full_unstemmed | Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title_short | Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly |
title_sort | use of uv treated milk powder to increase vaccine efficacy in the elderly |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200024/ https://www.ncbi.nlm.nih.gov/pubmed/30386327 http://dx.doi.org/10.3389/fimmu.2018.02254 |
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