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Efficacy of D,L-methadone in the treatment of glioblastoma in vitro

AIM: Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM). METHODS: We analyzed the μ-opioid receptor expression in a set of GBM cell lines and investigated the efficacy of D,L-methadone alone and in combination with temozolomide (TMZ). RESULTS & CONCLUSION: E...

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Detalles Bibliográficos
Autores principales:	Brawanski, Konstantin, Brockhoff, Gero, Hau, Peter, Vollmann-Zwerenz, Arabel, Freyschlag, Christian, Lohmeier, Annette, Riemenschneider, Markus J, Thomé, Claudius, Brawanski, Alexander, Proescholdt, Martin A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200059/ https://www.ncbi.nlm.nih.gov/pubmed/29916277 http://dx.doi.org/10.2217/cns-2018-0006

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