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Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration

BACKGROUND: Several intracellular signaling pathways that are deregulated during hepatocarcinogenesis might constitute potential targets for hepatocellular carcinoma (HCC) therapy. The aim of this study was to test the potential synergic antitumor effect of salirasib and sorafenib in a diethylnitros...

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Detalles Bibliográficos
Autores principales:	Ciccarelli, Olga, Colson, Arthur, De Saeger, Christine, Reding, Raymond, Sempoux, Christine, Leclercq, Isabelle A, Stärkel, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200087/ https://www.ncbi.nlm.nih.gov/pubmed/30410370 http://dx.doi.org/10.2147/OTT.S176903

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