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Intranasal niosomes of nefopam with improved bioavailability: preparation, optimization, and in-vivo evaluation

OBJECTIVE: One of the greatest challenges drug formulation is facing is poor bioavailability via oral route. In this regard, nasal drug delivery has been commonly used as an alternative route to improve drug bioavailability. Nefopam hydrochloride (NF) is an analgesic drug that suffers from poor bioa...

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Detalles Bibliográficos
Autores principales:	Abou-Taleb, Heba A, Khallaf, Rasha A, Abdel-Aleem, Jelan A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200089/ https://www.ncbi.nlm.nih.gov/pubmed/30410310 http://dx.doi.org/10.2147/DDDT.S177746

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