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Opioid analgesia and the somatosensory memory of neonatal surgical injury in the adult rat

BACKGROUND: Nociceptive input during early development can produce somatosensory memory that influences future pain response. Hind-paw incision during the 1st postnatal week in the rat enhances re-incision hyperalgesia in adulthood. We now evaluate its modulation by neonatal analgesia. METHODS: Neon...

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Detalles Bibliográficos
Autores principales: Moriarty, O., Harrington, L., Beggs, S., Walker, S.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200106/
https://www.ncbi.nlm.nih.gov/pubmed/29935586
http://dx.doi.org/10.1016/j.bja.2017.11.111