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Opioid analgesia and the somatosensory memory of neonatal surgical injury in the adult rat
BACKGROUND: Nociceptive input during early development can produce somatosensory memory that influences future pain response. Hind-paw incision during the 1st postnatal week in the rat enhances re-incision hyperalgesia in adulthood. We now evaluate its modulation by neonatal analgesia. METHODS: Neon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200106/ https://www.ncbi.nlm.nih.gov/pubmed/29935586 http://dx.doi.org/10.1016/j.bja.2017.11.111 |