Cargando…
Facilitation of IL-22 production from innate lymphoid cells by prostaglandin E(2) prevents experimental lung neutrophilic inflammation
Acute lung injury is a neutrophil-dominant, life-threatening disease without effective therapies and better understanding of the pathophysiological mechanisms involved is an urgent need. Here we show that interleukin (IL)-22 is produced from innate lymphoid cells (ILC) and is responsible for suppres...
Autores principales: | Felton, Jennifer M, Duffin, Rodger, Robb, Calum T, Crittenden, Siobhan, Anderton, Stephen M, Howie, Sarah E M, Whyte, Moira K B, Rossi, Adriano G, Yao, Chengcan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200127/ https://www.ncbi.nlm.nih.gov/pubmed/29574419 http://dx.doi.org/10.1136/thoraxjnl-2017-211097 |
Ejemplares similares
-
Purine metabolism controls innate lymphoid cell function and protects against intestinal injury
por: Crittenden, Siobhan, et al.
Publicado: (2018) -
Non‐steroidal anti‐inflammatory drugs, prostaglandins, and COVID‐19
por: Robb, Calum T., et al.
Publicado: (2020) -
Prostaglandin E(2) directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF‐β signalling
por: Goepp, Marie, et al.
Publicado: (2021) -
Prostaglandin E(2) promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
por: Crittenden, Siobhan, et al.
Publicado: (2021) -
Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
por: Gray, Robert D, et al.
Publicado: (2018)