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Co-localization of plaque macrophages with calcification is associated with a more vulnerable plaque phenotype and a greater calcification burden in coronary target segments as determined by OCT

BACKGROUND: The presence of plaque macrophages and microcalcifications are acknowledged features of plaque vulnerability. Experimental data suggest that microcalcifications promote inflammation and macrophages foster microcalcifications. However, co-localization of plaque macrophages and calcificati...

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Detalles Bibliográficos
Autores principales: Burgmaier, Mathias, Milzi, Andrea, Dettori, Rosalia, Burgmaier, Kathrin, Marx, Nikolaus, Reith, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200236/
https://www.ncbi.nlm.nih.gov/pubmed/30356326
http://dx.doi.org/10.1371/journal.pone.0205984

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