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Co-localization of plaque macrophages with calcification is associated with a more vulnerable plaque phenotype and a greater calcification burden in coronary target segments as determined by OCT
BACKGROUND: The presence of plaque macrophages and microcalcifications are acknowledged features of plaque vulnerability. Experimental data suggest that microcalcifications promote inflammation and macrophages foster microcalcifications. However, co-localization of plaque macrophages and calcificati...
Autores principales: | Burgmaier, Mathias, Milzi, Andrea, Dettori, Rosalia, Burgmaier, Kathrin, Marx, Nikolaus, Reith, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200236/ https://www.ncbi.nlm.nih.gov/pubmed/30356326 http://dx.doi.org/10.1371/journal.pone.0205984 |
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