Genome amplification and cellular senescence are hallmarks of human placenta development

Genome amplification and cellular senescence are commonly associated with pathological processes. While physiological roles for polyploidization and senescence have been described in mouse development, controversy exists over their significance in humans. Here, we describe tetraploidization and sene...

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Detalles Bibliográficos
Autores principales: Velicky, Philipp, Meinhardt, Gudrun, Plessl, Kerstin, Vondra, Sigrid, Weiss, Tamara, Haslinger, Peter, Lendl, Thomas, Aumayr, Karin, Mairhofer, Mario, Zhu, Xiaowei, Schütz, Birgit, Hannibal, Roberta L., Lindau, Robert, Weil, Beatrix, Ernerudh, Jan, Neesen, Jürgen, Egger, Gerda, Mikula, Mario, Röhrl, Clemens, Urban, Alexander E., Baker, Julie, Knöfler, Martin, Pollheimer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200260/
https://www.ncbi.nlm.nih.gov/pubmed/30312291
http://dx.doi.org/10.1371/journal.pgen.1007698

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