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Increased Trimethylation of histone H3K36 associates with biliary differentiation and predicts poor prognosis in resectable hepatocellular carcinoma

INTRODUCTION: Trimethylation of histone H3K36 (H3K36me3), an epigenetic marker of transcription-associated histone modification and stem cell regulation, is expressed in a variety of human cancers. This study elucidated the prognostic significance of H3K36me3 in patients with resectable hepatocellul...

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Detalles Bibliográficos
Autores principales:	Lien, Huang-Chun, Jeng, Yung-Ming, Jhuang, Yu-Ling, Yuan, Ray-Hwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200274/ https://www.ncbi.nlm.nih.gov/pubmed/30356299 http://dx.doi.org/10.1371/journal.pone.0206261

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