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Single-molecule observation of nucleotide induced conformational changes in basal SecA-ATP hydrolysis

SecA is the critical adenosine triphosphatase that drives preprotein transport through the translocon, SecYEG, in Escherichia coli. This process is thought to be regulated by conformational changes of specific domains of SecA, but real-time, real-space measurement of these changes is lacking. We use...

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Detalles Bibliográficos
Autores principales:	Chada, Nagaraju, Chattrakun, Kanokporn, Marsh, Brendan P., Mao, Chunfeng, Bariya, Priya, King, Gavin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200364/ https://www.ncbi.nlm.nih.gov/pubmed/30397644 http://dx.doi.org/10.1126/sciadv.aat8797

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