Cargando…
Phosphaturic mesenchymal tumor and related wound problem
INTRODUCTION: Phosphaturic mesenchymal tumor mixed connective tissue type (PMT/MCT) is the most common type (up to 90%) of phosphaturic mesenchymal tumor (PMT), a rare clinicopathologic entity. Besides overproduction of fibroblast growth factor 23 (FGF23), there is a big variation of immunohistochem...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200523/ https://www.ncbi.nlm.nih.gov/pubmed/30290606 http://dx.doi.org/10.1097/MD.0000000000012507 |
_version_ | 1783365345134772224 |
---|---|
author | Xiao, Xian Sun, Xiaofang Ni, Pengwen Huang, Yao Xie, Ting |
author_facet | Xiao, Xian Sun, Xiaofang Ni, Pengwen Huang, Yao Xie, Ting |
author_sort | Xiao, Xian |
collection | PubMed |
description | INTRODUCTION: Phosphaturic mesenchymal tumor mixed connective tissue type (PMT/MCT) is the most common type (up to 90%) of phosphaturic mesenchymal tumor (PMT), a rare clinicopathologic entity. Besides overproduction of fibroblast growth factor 23 (FGF23), there is a big variation of immunohistochemical characteristic across types of PMT, which makes it difficult to obtain an early diagnosis of PMT/MCT. As a benign tumor, PMT/MCT usually happens in subcutaneous tissues and leads to nonhealing of wound. A complete excision of PMT/MCT facilitates wound healing. CONCLUSIONS: Review of the existing evidence indicates that early diagnosis of PMT/MCT is critically important when treating PMT/MCT wound. Hence standardization of early diagnosis for PMT/MCT is mandated. |
format | Online Article Text |
id | pubmed-6200523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-62005232018-11-07 Phosphaturic mesenchymal tumor and related wound problem Xiao, Xian Sun, Xiaofang Ni, Pengwen Huang, Yao Xie, Ting Medicine (Baltimore) Research Article INTRODUCTION: Phosphaturic mesenchymal tumor mixed connective tissue type (PMT/MCT) is the most common type (up to 90%) of phosphaturic mesenchymal tumor (PMT), a rare clinicopathologic entity. Besides overproduction of fibroblast growth factor 23 (FGF23), there is a big variation of immunohistochemical characteristic across types of PMT, which makes it difficult to obtain an early diagnosis of PMT/MCT. As a benign tumor, PMT/MCT usually happens in subcutaneous tissues and leads to nonhealing of wound. A complete excision of PMT/MCT facilitates wound healing. CONCLUSIONS: Review of the existing evidence indicates that early diagnosis of PMT/MCT is critically important when treating PMT/MCT wound. Hence standardization of early diagnosis for PMT/MCT is mandated. Wolters Kluwer Health 2018-10-05 /pmc/articles/PMC6200523/ /pubmed/30290606 http://dx.doi.org/10.1097/MD.0000000000012507 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Xiao, Xian Sun, Xiaofang Ni, Pengwen Huang, Yao Xie, Ting Phosphaturic mesenchymal tumor and related wound problem |
title | Phosphaturic mesenchymal tumor and related wound problem |
title_full | Phosphaturic mesenchymal tumor and related wound problem |
title_fullStr | Phosphaturic mesenchymal tumor and related wound problem |
title_full_unstemmed | Phosphaturic mesenchymal tumor and related wound problem |
title_short | Phosphaturic mesenchymal tumor and related wound problem |
title_sort | phosphaturic mesenchymal tumor and related wound problem |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200523/ https://www.ncbi.nlm.nih.gov/pubmed/30290606 http://dx.doi.org/10.1097/MD.0000000000012507 |
work_keys_str_mv | AT xiaoxian phosphaturicmesenchymaltumorandrelatedwoundproblem AT sunxiaofang phosphaturicmesenchymaltumorandrelatedwoundproblem AT nipengwen phosphaturicmesenchymaltumorandrelatedwoundproblem AT huangyao phosphaturicmesenchymaltumorandrelatedwoundproblem AT xieting phosphaturicmesenchymaltumorandrelatedwoundproblem |