Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations

Kv1.2 is a prominent voltage-gated potassium channel that influences action potential generation and propagation in the central nervous system. We explored multi-protein complexes containing Kv1.2 using mass spectrometry followed by screening for effects on Kv1.2. We report that Slc7a5, a neutral am...

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Detalles Bibliográficos
Autores principales: Baronas, Victoria A., Yang, Runying Y., Morales, Luis Carlos, Sipione, Simonetta, Kurata, Harley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200743/
https://www.ncbi.nlm.nih.gov/pubmed/30356053
http://dx.doi.org/10.1038/s41467-018-06859-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200743/
https://www.ncbi.nlm.nih.gov/pubmed/30356053
http://dx.doi.org/10.1038/s41467-018-06859-x

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