Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations

While the incidence of esophageal adenocarcinoma (EAC) has risen drastically in Western countries over the last 40 years, a similar trend has not been observed for EAC in China. Here, we analyzed mutational spectrum, copy number alterations, and structural variants from whole-genome sequencing of 10...

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Detalles Bibliográficos
Autores principales: Dai, James Y., Wang, Xiaoyu, Buas, Matthew F., Zhang, Chengjuan, Ma, Jie, Wei, Bing, Li, Yin, Zhao, Baosheng, Hyun, Teresa S., Chen, Xueyan, Loeb, Keith R., Odze, Robert, Yao, Lena, Sun, Xin, Self, Steve, Vaughan, Thomas L., Guo, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200836/
https://www.ncbi.nlm.nih.gov/pubmed/30374464
http://dx.doi.org/10.1038/s42003-018-0182-8

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