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A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing

As human body finite element models become more integrated with the design of safety countermeasures and regulations, novel models need to be developed that reflect the variation in the population's anthropometry. However, these new models may be missing information which will need to be transl...

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Autores principales: Giudice, J. Sebastian, Poulard, David, Nie, Bingbing, Wu, Taotao, Panzer, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200845/
https://www.ncbi.nlm.nih.gov/pubmed/30406094
http://dx.doi.org/10.3389/fbioe.2018.00149
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author Giudice, J. Sebastian
Poulard, David
Nie, Bingbing
Wu, Taotao
Panzer, Matthew B.
author_facet Giudice, J. Sebastian
Poulard, David
Nie, Bingbing
Wu, Taotao
Panzer, Matthew B.
author_sort Giudice, J. Sebastian
collection PubMed
description As human body finite element models become more integrated with the design of safety countermeasures and regulations, novel models need to be developed that reflect the variation in the population's anthropometry. However, these new models may be missing information which will need to be translated from existing models. During the development of a 5th percentile female occupant model (F05), cortical thickness information of the coxal bone was unavailable due to resolution limits in the computed tomography (CT) scans. In this study, a method for transferring cortical thickness information from a source to a target model with entirely different geometry and architecture is presented. The source and target models were the Global Human Body Models Consortium (GHBMC) 50th percentile male (M50) and F05 coxal bones, respectively. To project the coxal bone cortical thickness from the M50 to the F05, the M50 model was first morphed using a Kriging method with 132 optimized control points to the F05 anthropometry. This technique was found to be accurate with a mean nodal discrepancy of 1.27 mm between the F05 and morphed M50 (mM50) coxal bones. Cortical thickness at each F05 node was determined by taking the average cortical thickness of every mM50 node, non-linearly weighted by its distance to the F05 nodes. The non-linear weighting coefficient, β, had a large effect on the accuracy and smoothness of the projected cortical bone thickness. The optimal projection had β = 4 and was defined when the tradeoff between projection accuracy and smoothness was equal. Finally, a quasi-static pelvis compression was simulated to examine to effect of β. As β, increased from 0 to 4, the failure force decreased by ~100 N, whereas the failure displacement increased by 0.9 mm. Results from quasi-static compression tests of the F05 pelvis were comparable to experimental results. This method could be applied to other anatomical regions where cortical thickness variation is important, such as the femur and ribs and is not limited to GHBMC-family models. Furthermore, this process will aid the development of subject-specific finite element models where accurate cortical bone thickness measurements cannot be obtained.
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spelling pubmed-62008452018-11-07 A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing Giudice, J. Sebastian Poulard, David Nie, Bingbing Wu, Taotao Panzer, Matthew B. Front Bioeng Biotechnol Bioengineering and Biotechnology As human body finite element models become more integrated with the design of safety countermeasures and regulations, novel models need to be developed that reflect the variation in the population's anthropometry. However, these new models may be missing information which will need to be translated from existing models. During the development of a 5th percentile female occupant model (F05), cortical thickness information of the coxal bone was unavailable due to resolution limits in the computed tomography (CT) scans. In this study, a method for transferring cortical thickness information from a source to a target model with entirely different geometry and architecture is presented. The source and target models were the Global Human Body Models Consortium (GHBMC) 50th percentile male (M50) and F05 coxal bones, respectively. To project the coxal bone cortical thickness from the M50 to the F05, the M50 model was first morphed using a Kriging method with 132 optimized control points to the F05 anthropometry. This technique was found to be accurate with a mean nodal discrepancy of 1.27 mm between the F05 and morphed M50 (mM50) coxal bones. Cortical thickness at each F05 node was determined by taking the average cortical thickness of every mM50 node, non-linearly weighted by its distance to the F05 nodes. The non-linear weighting coefficient, β, had a large effect on the accuracy and smoothness of the projected cortical bone thickness. The optimal projection had β = 4 and was defined when the tradeoff between projection accuracy and smoothness was equal. Finally, a quasi-static pelvis compression was simulated to examine to effect of β. As β, increased from 0 to 4, the failure force decreased by ~100 N, whereas the failure displacement increased by 0.9 mm. Results from quasi-static compression tests of the F05 pelvis were comparable to experimental results. This method could be applied to other anatomical regions where cortical thickness variation is important, such as the femur and ribs and is not limited to GHBMC-family models. Furthermore, this process will aid the development of subject-specific finite element models where accurate cortical bone thickness measurements cannot be obtained. Frontiers Media S.A. 2018-10-18 /pmc/articles/PMC6200845/ /pubmed/30406094 http://dx.doi.org/10.3389/fbioe.2018.00149 Text en Copyright © 2018 Giudice, Poulard, Nie, Wu and Panzer. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Giudice, J. Sebastian
Poulard, David
Nie, Bingbing
Wu, Taotao
Panzer, Matthew B.
A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title_full A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title_fullStr A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title_full_unstemmed A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title_short A Cortical Thickness Mapping Method for the Coxal Bone Using Morphing
title_sort cortical thickness mapping method for the coxal bone using morphing
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200845/
https://www.ncbi.nlm.nih.gov/pubmed/30406094
http://dx.doi.org/10.3389/fbioe.2018.00149
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