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CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques

A major issue for present HIV-1 research is to establish model systems that reflect or mimic viral replication and pathogenesis actually observed in infected humans. To this end, various strategies using macaques as infection targets have long been pursued. In particular, experimental infections of...

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Detalles Bibliográficos
Autores principales: Doi, Naoya, Miura, Tomoyuki, Mori, Hiromi, Sakawaki, Hiromi, Koma, Takaaki, Adachi, Akio, Nomaguchi, Masako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200915/
https://www.ncbi.nlm.nih.gov/pubmed/30405570
http://dx.doi.org/10.3389/fmicb.2018.02510