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Calcimimetic R568 reduced the blood pressure and improved aortic remodeling in spontaneously hypertensive rats by inhibiting local renin-angiotensin system activity

Hypertension is a cardiovascular disease that seriously affects human health. Activation of the calcium-sensing receptor (CaSR) inhibits cyclic adenosine monophosphate (cAMP) formation by increasing [Ca(2+)](i) and subsequently inhibiting renin release. The renin-angiotensin system (RAS) plays an im...

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Detalles Bibliográficos
Autores principales:	Sun, Ruixia, Zhang, Wenwen, Zhong, Hua, Wang, Lamei, Tang, Na, Liu, Yongmin, Zhao, Yongli, Zhang, Tian, He, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200994/ https://www.ncbi.nlm.nih.gov/pubmed/30402152 http://dx.doi.org/10.3892/etm.2018.6734

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