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Randomized, Double-Blind, Placebo-Controlled Studies of the Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Eravacycline

Eravacycline is a novel, fully synthetic fluorocycline antibiotic with in vitro activity against aerobic and anaerobic Gram-positive and Gram-negative pathogens, including multidrug-resistant (MDR) bacteria. The pharmacokinetics (PK), urinary excretion, and safety/tolerability of intravenous (i.v.)...

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Detalles Bibliográficos
Autores principales:	Newman, Joseph V., Zhou, Jian, Izmailyan, Sergey, Tsai, Larry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201080/ https://www.ncbi.nlm.nih.gov/pubmed/30150464 http://dx.doi.org/10.1128/AAC.01174-18

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