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A polymorphism rs3746444 within the pre‐miR‐499 alters the maturation of miR‐499‐5p and its antiapoptotic function

microRNAs (miRNAs) are non‐coding RNAs that function as post‐transcriptional regulators of cardiac development and cardiovascular diseases. Single nucleotide polymorphisms (SNPs) in miRNA genes are a novel class of genetic variations in the human genome that confer the risk of cardiovascular disease...

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Detalles Bibliográficos
Autores principales: Ding, Wei, Li, Mengyang, Sun, Teng, Han, Di, Guo, Xiaoci, Chen, Xiao, Wan, Qinggong, Zhang, Xuejuan, Wang, Jianxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201352/
https://www.ncbi.nlm.nih.gov/pubmed/30102014
http://dx.doi.org/10.1111/jcmm.13813