Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases

Sirtuin3 (SIRT3) is associated with oxidative stress and lifespan. However, the possible mechanisms underlying its influence are unknown. We hypothesized that SIRT3 increases the antioxidant capacity of aged cells and improves the efficacy of human mesenchymal stem cell (hMSC) therapy for ischaemic...

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Detalles Bibliográficos
Autores principales: Zhang, Dong‐Yang, Zhang, Chun‐Feng, Fu, Bi‐Cheng, Sun, Lu, Wang, Xue‐Qing, Chen, Wei, Liu, Wei, Liu, Kai‐Yu, Du, Guo‐Qing, Ma, Chong‐Yi, Jiang, Shu‐Lin, Li, Ren‐Ke, Tian, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201360/
https://www.ncbi.nlm.nih.gov/pubmed/30091830
http://dx.doi.org/10.1111/jcmm.13821

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