Effects of interleukin‐17A in nucleus pulposus cells and its small‐molecule inhibitors for intervertebral disc disease

Intervertebral discs (IVD) degeneration, which is caused by ageing or mechanical stress, leads to IVD disease, including back pain and sciatica. The cytokine interleukin (IL)‐17A is elevated in NP cells during IVD disease. Here we explored the pharmacotherapeutic potential of IL‐17A for the treatmen...

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Detalles Bibliográficos
Autores principales: Suyama, Kaori, Sakai, Daisuke, Hirayama, Noriaki, Nakamura, Yoshihiko, Matsushita, Erika, Terayama, Hayato, Qu, Ning, Tanaka, Osamu, Sakabe, Kou, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201370/
https://www.ncbi.nlm.nih.gov/pubmed/30207057
http://dx.doi.org/10.1111/jcmm.13828

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