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Isobavachalcone sensitizes cells to E2‐induced paclitaxel resistance by down‐regulating CD44 expression in ER+ breast cancer cells

Oestrogen receptor (ER) is expressed in approximately 60%‐70% of human breast cancer. Clinical trials and retrospective analyses have shown that ER‐positive (ER+) tumours are more tolerant to chemotherapeutic drug resistance than ER‐negative (ER−) tumours. In addition, isobavachalcone (IBC) is known...

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Detalles Bibliográficos
Autores principales: Shi, Junfeng, Chen, Yi, Chen, Wenxing, Tang, Cuiju, Zhang, Honghong, Chen, Yuetong, Yang, Xiuwei, Xu, Zhi, Wei, Jingsun, Chen, Jinfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201375/
https://www.ncbi.nlm.nih.gov/pubmed/30179299
http://dx.doi.org/10.1111/jcmm.13719