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Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice

BACKGROUND: Exposure of rodents to chronic high-fat diet (HFD) results in upregulation of inflammatory markers and proliferation of microglia within the mediobasal hypothalamus. Such hypothalamic inflammation is associated with metabolic dysfunction, central leptin resistance, and maintenance of obe...

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Detalles Bibliográficos
Autores principales: Herrick, Mary K., Favela, Kristin M., Simerly, Richard B., Abumrad, Naji N., Bingham, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201532/
https://www.ncbi.nlm.nih.gov/pubmed/30355312
http://dx.doi.org/10.1186/s10020-018-0057-y