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Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome

BACKGROUND: Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensitizing action. Gestational diabetes mellitus (GDM) is characterized by insulin resistance leading to materno-fetal hyperglycemia and detrimental birth outcomes. By investigating paired subcutaneous (S...

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Detalles Bibliográficos
Autores principales: Ott, Raffael, Stupin, Jens H., Melchior, Kerstin, Schellong, Karen, Ziska, Thomas, Dudenhausen, Joachim W., Henrich, Wolfgang, Rancourt, Rebecca C., Plagemann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201547/
https://www.ncbi.nlm.nih.gov/pubmed/30355290
http://dx.doi.org/10.1186/s13148-018-0567-z