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Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression

BACKGROUND: HOTAIR was known to enhance radioresistance in several cancers. However, the function of HOTAIR on radioresistance involving the regulation of HIF-1α in cervical cancer has not been reported. METHODS: BALB/c nude mice were injected subcutaneously with HeLa cells and irradiated by X-ray....

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Detalles Bibliográficos
Autores principales: Li, Ning, Meng, Dan-dan, Gao, Ling, Xu, Yue, Liu, Pei-jie, Tian, Yong-wei, Yi, Zhen-ying, Zhang, Yan, Tie, Xiao-jing, Xu, Zhi-qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201557/
https://www.ncbi.nlm.nih.gov/pubmed/30355300
http://dx.doi.org/10.1186/s13014-018-1153-4

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