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Interprétation délicate de l'immunofixation des protéines sériques

Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each tra...

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Autores principales: Karfo, Raoul, Kabré, Elie, Safir, Nadia, Bouabdellah, Mounya, Benchekroun, Laila, Sakandé, Jean, Chabraoui, Layachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201619/
https://www.ncbi.nlm.nih.gov/pubmed/30374376
http://dx.doi.org/10.11604/pamj.2018.30.130.13662
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author Karfo, Raoul
Kabré, Elie
Safir, Nadia
Bouabdellah, Mounya
Benchekroun, Laila
Sakandé, Jean
Chabraoui, Layachi
author_facet Karfo, Raoul
Kabré, Elie
Safir, Nadia
Bouabdellah, Mounya
Benchekroun, Laila
Sakandé, Jean
Chabraoui, Layachi
author_sort Karfo, Raoul
collection PubMed
description Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each track, in the second case we report a case of double monoclonal band on immunofixation electrophoresis. Reducing agent such as β2-mercaptoethanol used in these two cases allowed to solve the problem and to make a diagnosis. A comparison between clinical radiological and laboratory test data is necessary before making a diagnosis of monoclonal immunoglobulin.
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spelling pubmed-62016192018-10-29 Interprétation délicate de l'immunofixation des protéines sériques Karfo, Raoul Kabré, Elie Safir, Nadia Bouabdellah, Mounya Benchekroun, Laila Sakandé, Jean Chabraoui, Layachi Pan Afr Med J Case Series Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each track, in the second case we report a case of double monoclonal band on immunofixation electrophoresis. Reducing agent such as β2-mercaptoethanol used in these two cases allowed to solve the problem and to make a diagnosis. A comparison between clinical radiological and laboratory test data is necessary before making a diagnosis of monoclonal immunoglobulin. The African Field Epidemiology Network 2018-06-14 /pmc/articles/PMC6201619/ /pubmed/30374376 http://dx.doi.org/10.11604/pamj.2018.30.130.13662 Text en © Raoul Karfo et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Karfo, Raoul
Kabré, Elie
Safir, Nadia
Bouabdellah, Mounya
Benchekroun, Laila
Sakandé, Jean
Chabraoui, Layachi
Interprétation délicate de l'immunofixation des protéines sériques
title Interprétation délicate de l'immunofixation des protéines sériques
title_full Interprétation délicate de l'immunofixation des protéines sériques
title_fullStr Interprétation délicate de l'immunofixation des protéines sériques
title_full_unstemmed Interprétation délicate de l'immunofixation des protéines sériques
title_short Interprétation délicate de l'immunofixation des protéines sériques
title_sort interprétation délicate de l'immunofixation des protéines sériques
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201619/
https://www.ncbi.nlm.nih.gov/pubmed/30374376
http://dx.doi.org/10.11604/pamj.2018.30.130.13662
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