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Interprétation délicate de l'immunofixation des protéines sériques
Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each tra...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201619/ https://www.ncbi.nlm.nih.gov/pubmed/30374376 http://dx.doi.org/10.11604/pamj.2018.30.130.13662 |
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author | Karfo, Raoul Kabré, Elie Safir, Nadia Bouabdellah, Mounya Benchekroun, Laila Sakandé, Jean Chabraoui, Layachi |
author_facet | Karfo, Raoul Kabré, Elie Safir, Nadia Bouabdellah, Mounya Benchekroun, Laila Sakandé, Jean Chabraoui, Layachi |
author_sort | Karfo, Raoul |
collection | PubMed |
description | Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each track, in the second case we report a case of double monoclonal band on immunofixation electrophoresis. Reducing agent such as β2-mercaptoethanol used in these two cases allowed to solve the problem and to make a diagnosis. A comparison between clinical radiological and laboratory test data is necessary before making a diagnosis of monoclonal immunoglobulin. |
format | Online Article Text |
id | pubmed-6201619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-62016192018-10-29 Interprétation délicate de l'immunofixation des protéines sériques Karfo, Raoul Kabré, Elie Safir, Nadia Bouabdellah, Mounya Benchekroun, Laila Sakandé, Jean Chabraoui, Layachi Pan Afr Med J Case Series Immunofixation is currently very used in medical laboratories. The interpretation of the results is usually easy, but some cases raise interpretative problems. We here report two cases difficult to interpret. In the first case, we report a case of nonspecific precipitation of the protein on each track, in the second case we report a case of double monoclonal band on immunofixation electrophoresis. Reducing agent such as β2-mercaptoethanol used in these two cases allowed to solve the problem and to make a diagnosis. A comparison between clinical radiological and laboratory test data is necessary before making a diagnosis of monoclonal immunoglobulin. The African Field Epidemiology Network 2018-06-14 /pmc/articles/PMC6201619/ /pubmed/30374376 http://dx.doi.org/10.11604/pamj.2018.30.130.13662 Text en © Raoul Karfo et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Karfo, Raoul Kabré, Elie Safir, Nadia Bouabdellah, Mounya Benchekroun, Laila Sakandé, Jean Chabraoui, Layachi Interprétation délicate de l'immunofixation des protéines sériques |
title | Interprétation délicate de l'immunofixation des protéines sériques |
title_full | Interprétation délicate de l'immunofixation des protéines sériques |
title_fullStr | Interprétation délicate de l'immunofixation des protéines sériques |
title_full_unstemmed | Interprétation délicate de l'immunofixation des protéines sériques |
title_short | Interprétation délicate de l'immunofixation des protéines sériques |
title_sort | interprétation délicate de l'immunofixation des protéines sériques |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201619/ https://www.ncbi.nlm.nih.gov/pubmed/30374376 http://dx.doi.org/10.11604/pamj.2018.30.130.13662 |
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