Cargando…
The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability
Microtubules form from longitudinally and laterally assembling tubulin α/β-dimers. The assembly induces strain in tubulin, resulting in cycles of microtubule catastrophe and regrowth. This so-called dynamic instability is governed by GTP hydrolysis that renders the microtubule lattice unstable, but...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201834/ https://www.ncbi.nlm.nih.gov/pubmed/29967541 http://dx.doi.org/10.1038/s41594-018-0087-8 |