Genome-wide association analysis identifies SNPs predictive of in vitro leukemic cell sensitivity to cytarabine in pediatric AML

Cytarabine has been an integral part of acute myeloid leukemia (AML) chemotherapy for over four decades. However, development of resistance and high rates of relapse is a significant impediment in successfully treating AML. We performed a genome-wide association analysis (GWAS) and identified 113 (8...

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Detalles Bibliográficos
Autores principales: Bargal, Salma A., Rafiee, Roya, Crews, Kristine R., Wu, Huiyun, Cao, Xueyuan, Rubnitz, Jeffrey E., Ribeiro, Raul C., Downing, James R., Pounds, Stanley B., Lamba, Jatinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201857/
https://www.ncbi.nlm.nih.gov/pubmed/30405880
http://dx.doi.org/10.18632/oncotarget.26163

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