Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A(2) to exert its bactericidal effects

Human Group IIA secreted phospholipase A(2) (hGIIA) is an acute phase protein with bactericidal activity against Gram-positive bacteria. Infection models in hGIIA transgenic mice have suggested the importance of hGIIA as an innate defense mechanism against the human pathogens Group A Streptococcus (...

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Detalles Bibliográficos
Autores principales: van Hensbergen, Vincent P., Movert, Elin, de Maat, Vincent, Lüchtenborg, Christian, Le Breton, Yoann, Lambeau, Gérard, Payré, Christine, Henningham, Anna, Nizet, Victor, van Strijp, Jos A. G., Brügger, Britta, Carlsson, Fredric, McIver, Kevin S., van Sorge, Nina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201954/
https://www.ncbi.nlm.nih.gov/pubmed/30321240
http://dx.doi.org/10.1371/journal.ppat.1007348

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