Aspirin promotes apoptosis and inhibits proliferation by blocking G(0)/G(1) into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway

Rheumatoid arthritis (RA) is a commonly occurring autoimmune disease. Its defining pathological characteristic is the excessive proliferation of fibroblast-like synoviocytes (FLS), which is similar to tumor cells and results in a range of clinical problems. As a commonly used antipyretic, analgesic...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqi, Feng, Hao, Du, Juan, Sun, Jing, Li, Dongfang, Hasegawa, Tomoka, Amizuka, Norio, Li, Minqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202076/
https://www.ncbi.nlm.nih.gov/pubmed/30221683
http://dx.doi.org/10.3892/ijmm.2018.3883

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