Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1α/YAP signaling pathway

The Hippo-yes-associated protein (YAP) signaling pathway was previously identified to serve an important role in controlling chondrocyte differentiation and post-natal growth. Growth plate cartilage tissue is avascular, and hypoxia-inducible factor (HIF)-1α is essential for chondrocytes to maintain...

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Detalles Bibliográficos
Autores principales: Li, Hao, Li, Xiaojuan, Jing, Xingzhi, Li, Mi, Ren, Ye, Chen, Jingyuan, Yang, Caihong, Wu, Hua, Guo, Fengjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202095/
https://www.ncbi.nlm.nih.gov/pubmed/30320354
http://dx.doi.org/10.3892/ijmm.2018.3921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202095/
https://www.ncbi.nlm.nih.gov/pubmed/30320354
http://dx.doi.org/10.3892/ijmm.2018.3921

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