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Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1α/YAP signaling pathway
The Hippo-yes-associated protein (YAP) signaling pathway was previously identified to serve an important role in controlling chondrocyte differentiation and post-natal growth. Growth plate cartilage tissue is avascular, and hypoxia-inducible factor (HIF)-1α is essential for chondrocytes to maintain...
Autores principales: | Li, Hao, Li, Xiaojuan, Jing, Xingzhi, Li, Mi, Ren, Ye, Chen, Jingyuan, Yang, Caihong, Wu, Hua, Guo, Fengjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202095/ https://www.ncbi.nlm.nih.gov/pubmed/30320354 http://dx.doi.org/10.3892/ijmm.2018.3921 |
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