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Age-associated decline in Nrf2 signaling and associated mtDNA damage may be involved in the degeneration of the auditory cortex: Implications for central presbycusis

Central presbycusis is the most common sensory disorder in the elderly population, however, the underlying molecular mechanism remains unclear. NF-E2-related factor 2 (Nrf2) is a key transcription factor in the cellular response to oxidative stress, however, the role of Nrf2 in central presbycusis r...

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Detalles Bibliográficos
Autores principales: Li, Yongqin, Zhao, Xueyan, Hu, Yujuan, Sun, Haiying, He, Zuhong, Yuan, Jie, Cai, Hua, Sun, Yu, Huang, Xiang, Kong, Wen, Kong, Weijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202109/
https://www.ncbi.nlm.nih.gov/pubmed/30272261
http://dx.doi.org/10.3892/ijmm.2018.3907