RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer

We conducted an RNA sequencing study to identify novel gene fusions in 80 discovery dataset tumors collected from young patients with diffuse gastric cancer (DGC). Twenty-five in-frame fusions are associated with DGC, three of which (CLDN18-ARHGAP26, CTNND1-ARHGAP26, and ANXA2-MYO9A) are recurrent i...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hanna, Hong, Dongwan, Cho, Soo Young, Park, Young Soo, Ko, Woo Ri, Kim, Ju Hee, Hur, Hoon, Lee, Jongkeun, Kim, Su-Jin, Kwon, Sun Young, Lee, Jae-Hyuk, Park, Do Youn, Song, Kyu Sang, Chang, Heekyung, Ryu, Min-Hee, Cho, Kye Soo, Kang, Jeong Won, Kook, Myeong-Cherl, Thiessen, Nina, He, An, Mungall, Andy, Han, Sang-Uk, Kim, Hark Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202325/
https://www.ncbi.nlm.nih.gov/pubmed/30361512
http://dx.doi.org/10.1038/s41467-018-06747-4

Ejemplares similares

Ejemplares similares