circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma

Some types of circular RNA (circRNA) are aberrantly expressed in human diseases including hepatocellular carcinoma (HCC). However, its regulation mechanism and diagnostic roles are largely unknown. Here, we identified that circRNA_104075 (circ_104075) was highly expressed in HCC tissues, cell lines...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Xu, Yanfeng, Qian, Zijun, Zheng, Weisheng, Wu, Qi, Chen, Yan, Zhu, Guoqing, Liu, Ya, Bian, Zhixuan, Xu, Wen, Zhang, Yue, Sun, Fenyong, Pan, Qiuhui, Wang, Jiayi, Du, Lutao, Yu, Yongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202383/
https://www.ncbi.nlm.nih.gov/pubmed/30361504
http://dx.doi.org/10.1038/s41419-018-1132-6

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