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Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development
Parasites infect hosts in widely varying environments, encountering diverse challenges for adaptation. To identify malaria parasite genes under locally divergent selection across a large endemic region with a wide spectrum of transmission intensity, genome sequences were obtained from 284 clinical P...
Autores principales: | Duffy, Craig W., Amambua-Ngwa, Alfred, Ahouidi, Ambroise D., Diakite, Mahamadou, Awandare, Gordon A., Ba, Hampate, Tarr, Sarah J., Murray, Lee, Stewart, Lindsay B., D’Alessandro, Umberto, Otto, Thomas D., Kwiatkowski, Dominic P., Conway, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202401/ https://www.ncbi.nlm.nih.gov/pubmed/30361631 http://dx.doi.org/10.1038/s41598-018-34078-3 |
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