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Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

Extracorporeal life support (e.g., dialysis, extracorporeal membrane oxygenation (ECMO)) can affect drug disposition, placing patients at risk for therapeutic failure. In this population, dose selection to achieve safe and effective drug exposure is difficult. We developed a novel and flexible appro...

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Detalles Bibliográficos
Autores principales:	Watt, Kevin M., Cohen‐Wolkowiez, Michael, Barrett, Jeffrey S., Sevestre, Michael, Zhao, Ping, Brouwer, Kim L.R., Edginton, Andrea N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202466/ https://www.ncbi.nlm.nih.gov/pubmed/30033691 http://dx.doi.org/10.1002/psp4.12338

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