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Synthesis and pharmacological evaluation of novel epidermal growth factor receptor inhibitors against prostate tumor cells

The aim of the present study was to investigate the activities of novel synthetic epidermal growth factor receptor (EGFR) inhibitors (ZINC05463076, ZINC2102846 and ZINC19901103) against prostate tumors, in vitro models and investigate the potential underlying mechanisms. A panel of prostate tumor ce...

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Detalles Bibliográficos
Autores principales: Zhi, Yi, Wu, Xiaojun, Shen, Wenhao, Wang, Yongquan, Zhou, Xiaozhou, He, Peng, Pan, Jinhong, Chen, Zhiwen, Li, Weibing, Zhou, Zhansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202546/
https://www.ncbi.nlm.nih.gov/pubmed/30405791
http://dx.doi.org/10.3892/ol.2018.9438