Targeting Long Noncoding RNA in Glioma: A Pathway Perspective

Long noncoding RNAs (lncRNAs) participate extensively in biological processes of various cancers. The majority of these transcripts are uniquely expressed in differentiated tissues or specific cancer types. lncRNAs are aberrantly expressed in gliomas and exert diverse functions. In this article, we...

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Detalles Bibliográficos
Autores principales: Li, Junyang, Zhu, Yihao, Wang, Handong, Ji, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202792/
https://www.ncbi.nlm.nih.gov/pubmed/30388617
http://dx.doi.org/10.1016/j.omtn.2018.09.023
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author Li, Junyang
Zhu, Yihao
Wang, Handong
Ji, Xiangjun
author_facet Li, Junyang
Zhu, Yihao
Wang, Handong
Ji, Xiangjun
author_sort Li, Junyang
collection PubMed
description Long noncoding RNAs (lncRNAs) participate extensively in biological processes of various cancers. The majority of these transcripts are uniquely expressed in differentiated tissues or specific cancer types. lncRNAs are aberrantly expressed in gliomas and exert diverse functions. In this article, we provided an overview of how lncRNAs regulate cellular processes in glioma, enumerated the lncRNAs that may act as glioma biomarkers, and showed their potential clinical implications.
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spelling pubmed-62027922018-11-05 Targeting Long Noncoding RNA in Glioma: A Pathway Perspective Li, Junyang Zhu, Yihao Wang, Handong Ji, Xiangjun Mol Ther Nucleic Acids Article Long noncoding RNAs (lncRNAs) participate extensively in biological processes of various cancers. The majority of these transcripts are uniquely expressed in differentiated tissues or specific cancer types. lncRNAs are aberrantly expressed in gliomas and exert diverse functions. In this article, we provided an overview of how lncRNAs regulate cellular processes in glioma, enumerated the lncRNAs that may act as glioma biomarkers, and showed their potential clinical implications. American Society of Gene & Cell Therapy 2018-10-02 /pmc/articles/PMC6202792/ /pubmed/30388617 http://dx.doi.org/10.1016/j.omtn.2018.09.023 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Li, Junyang
Zhu, Yihao
Wang, Handong
Ji, Xiangjun
Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title_full Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title_fullStr Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title_full_unstemmed Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title_short Targeting Long Noncoding RNA in Glioma: A Pathway Perspective
title_sort targeting long noncoding rna in glioma: a pathway perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202792/
https://www.ncbi.nlm.nih.gov/pubmed/30388617
http://dx.doi.org/10.1016/j.omtn.2018.09.023
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AT jixiangjun targetinglongnoncodingrnaingliomaapathwayperspective

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