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High level in vivo mucin-type glycosylation in Escherichia coli
BACKGROUND: Increasing efforts have been made to assess the potential of Escherichia coli strains for the production of complex recombinant proteins. Since a considerable part of therapeutic proteins are glycoproteins, the lack of the post-translational attachment of sugar moieties in standard E. co...
Autores principales: | Mueller, Phillipp, Gauttam, Rahul, Raab, Nadja, Handrick, René, Wahl, Claudia, Leptihn, Sebastian, Zorn, Michael, Kussmaul, Michaela, Scheffold, Marianne, Eikmanns, Bernhard, Elling, Lothar, Gaisser, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202839/ https://www.ncbi.nlm.nih.gov/pubmed/30367634 http://dx.doi.org/10.1186/s12934-018-1013-9 |
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