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Mesenchymal stromal cells from myelodysplastic and acute myeloid leukemia patients display in vitro reduced proliferative potential and similar capacity to support leukemia cell survival

BACKGROUND: Mesenchymal stromal cells (MSCs) are an essential element of the bone marrow (BM) microenvironment, playing a crucial function in regulating hematopoietic stem cell proliferation and differentiation. Recent findings have outlined a putative role for MSCs in hematological malignancy devel...

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Detalles Bibliográficos
Autores principales:	Corradi, Giulia, Baldazzi, Carmen, Očadlíková, Darina, Marconi, Giovanni, Parisi, Sarah, Testoni, Nicoletta, Finelli, Carlo, Cavo, Michele, Curti, Antonio, Ciciarello, Marilena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202844/ https://www.ncbi.nlm.nih.gov/pubmed/30359303 http://dx.doi.org/10.1186/s13287-018-1013-z

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