Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia

Neonatal platelets are hypo-reactive to the tyrosine kinase-linked receptor agonist collagen. Here, we have investigated whether the hypo-responsiveness is related to altered levels of glycoprotein VI (GPVI) and integrin α2β1, or to defects in downstream signalling events by comparison to platelet a...

Descripción completa

Detalles Bibliográficos
Autores principales: Hardy, Alexander T., Palma-Barqueros, Verónica, Watson, Stephanie K., Malcor, Jean-Daniel, Eble, Johannes A., Gardiner, Elizabeth E., Blanco, José E., Guijarro-Campillo, Rafael, Delgado, Juan L., Lozano, María L., Teruel-Montoya, Raúl, Vicente, Vicente, Watson, Steve P., Rivera, José, Ferrer-Marín, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Schattauer GmbH 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202930/
https://www.ncbi.nlm.nih.gov/pubmed/29695020
http://dx.doi.org/10.1055/s-0038-1646924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202930/
https://www.ncbi.nlm.nih.gov/pubmed/29695020
http://dx.doi.org/10.1055/s-0038-1646924

Ejemplares similares